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doi: 10.1038/nature07813 52 YukJ-MKimTSKimSYLeeH-MHanJDufourCRet al

Sethi S, Murphy TF

The molecular mechanisms proposed to explain how ROS could specifically mediate brain damage are the following: (1) The lower levels of antioxidants can promote increased activity of lipoxygenase in CNS stimulating leukotriene production, thereby increasing the immunoinflammatory processes in the cerebral cortex

Singulett-Sauerstoff (O): Ein hochreaktives Sauerstoffmolekl, das durch antioxidative Prozesse wie die von GSH neutralisiert wird
