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Ezetimibe, which inhibits cholesterol transport protein (NPC1L1) [45]
It also boosts insulin secretion from the pancreas when blood sugar levels are high, and it also reduces glucose production in the liver (gluconeogenesis)
Though an interesting aspect of the cross-link formed in this case, is that it uses a non-terminal Glu to ligate to a non-terminal Lys, which seems to be rare in the process of forming an isopeptide bond
NICE guidance recommends intramuscular hydroxocobalamin as first-line treatment for B12 deficiency caused by pernicious anaemia or malabsorption

These receptors are crucial for controlling blood sugar and hunger
