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Authorship Contributions Sandro Gentile and and Felice Strollo prepared and wrote the paper

Targeted inhibition of NNMT improves insulin responsiveness and may protect against diet-induced obesity. Hong et al., Nature Medicine Longevity and Anti-Aging Potential Because NAD is vital for DNA repair, circadian rhythm regulation, and mitochondrial health, 5-Amino-1MQ is being explored as a geroprotective agent especially when stacked with NAD boosters or sirtuin activators

The exact mechanism of action of this drug is not fully understood at this time, but future research may contribute to deeper knowledge

doi: 10.3390/v10120712