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Human liver ALDH consists of at least 4 main isoenzymes, which are also present in many other tissues (Koivula, 1975

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Changes in the gut microbiome may significantly impact ME/CFS, potentially due to increased gut permeability that allows bacteria to enter the body, or through fermentation products affecting cells and immune responses, exacerbating cognitive and physical impairment in ME/CFS patients

Molecular mechanisms of developmental pathways in neurological disorders: A pharmacological and therapeutic review