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PLoS One 10:e0122358

Using Grx1roGFP2 we could not confirm these findings

Discussion Since the emergence of COVID-19 in 2019, the world has been in a state of contingency to fight the virus, which caused the death of more than 6 million people, and scientists around the world are racing to identify the risk factors associated with the pathogenic mechanism of COVID-19

At the same time, we present a review of recent studies on antioxidant interventions

For de novo NADPH synthesis pathway, correlation studies have revealed that thionicotinamide adenine dinucleotide (NADS) and thionicotinamide adenine dinucleotide phosphate (NADPS), converted from the pro-drug thionicotinamide (TN), act as inhibitors of NADKs through targeting the NAD-binding site of NADKs and decreasing the levels of NADPH