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Meaning lower doses keep their efficacy and avoiding the physiological side effects associated with increasing doses

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Dietary patterns most strongly associated with reduced cardiovascular risk include: Mediterranean diet diets rich in vegetables and fruit wholegrains legumes olive oil nuts oily fish Focus should fall on predominantly whole food dietary patterns that are balanced, high in fibre and low in saturated fats

With respect to fatty acid metabolism this yields dephosphorylated and inactive hormone sensitive lipase

New Trends Clin Neuropharmacol 1989;3(1):17-24
