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There have been negative effects observed as well, suggesting that DPI (and other related structures) act as pro-oxidants by decreasing GSH (Riganti et al., 2004)

Independent Evolution of SOD Families [edit source] Studies examining the phylogenetic distribution of SODs support the proposal that the major physiological function of SOD is to act as a protective mechanism among oxygen-metabolizing organisms against the formation of superoxide free radicals (McCord et al

Atherosclerosis Free radicals are involved in the atherogenic process

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