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1d), we did not observe differences at the protein level as assessed by immunofluorescence (Fig
ATP depletion activates ER stress (ERS) pathways [69, 70], leading to misfolded protein aggregation and redox imbalance if unresolved
Our findings in brain organoids with PSEN1 mutation complement well the results in human cortical organoids challenged with A that showed an increased expression of ferroptosis-promoting factors like Phkg243, Txnrd144 and Pparg42 [50]
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At this temperature, most lyophilized peptides remain stable for three to five years, with some maintaining viability even longer
