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Its job is specific: it inhibits an enzyme called NNMT nicotinamide N-methyltransferase that becomes overactive in fat tissue, especially as we age

Increases Metabolic Rate Without Muscle Loss AOD-9604 enhances metabolic efficiency by: Upregulating fat-metabolizing enzymes Increasing caloric expenditure at rest Sparing lean muscle massa critical factor in long-term weight management This is in contrast to traditional weight loss approaches, which often result in both fat and muscle loss, leading to a decrease in basal metabolic rate

Tissue-based map of the human proteome

AOD 9604 is a synthetic peptide derived from the C-terminal region of human growth hormone (GH fragment 176191), structurally modified with an N-terminal tyrosine residue to enhance stability in experimental systems