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Significant sex differences are observed in PD prevalence, with ASPR of 152.88 per 100,000 in males compared with 108.93 per 100,000 in females, yielding a maletofemale ratio ranging from 1.4 to 1.7 [35, 38] (see Table 1)

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Activation of the hypothalamicpituitaryadrenal (HPA) axis and subsequent release of glucocorticoid hormones is a key response that mobilizes fuel stores to meet energy demands 1,2,3,4,5

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[DOI] [PMC free article] [PubMed] [Google Scholar] 150.Qian J., LeSavage B.L., Hubka K.M., et al

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NAC supplementation did not affect TNF-, cortisol, 8-isoprostane, or SOD levels

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