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Selank tuftsin-PGP heptapeptide studied for anxiolytic and neuroimmune research, complementary to DSIP in stress-axis work

e , Induction of serum GDF15 in control and sensitized mice after the administration of the 5- lipoxygenase inhibitor zileuton during oral challenges with OVA (n = 5 control vehicle, 5 allergic vehicle, 5 control zileuton, 4 allergic zileuton)

This discrepancy challenges the assumption that anti-inflammatory activity alone is sufficient to reverse disease progression and suggests that metabolic and inflammatory pathways likely require simultaneous targeting