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While there is no evidence of common structural or functional brain alterations in PAIS, probably due to its heterogeneous origin and lack of conceptualization, ME/CFS has been extensively studied with MRI (magnetic resonance imaging), as recently reviewed by Nelson et al

After being thoroughly briefed on the study's objectives, procedures, and potential risks, all participants were informed and consented

A multicenter, double-blind small RCT involving 56 cirrhotic patients with acute HE who had been randomized to receive intravenous albumin (1.5 g/kg on day 1 and 1.0 g/kg on day 3) vs

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doi: 10.3390/nu12113371