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39 Most studies used B12 i.m., with slightly varying dosing regimens, commonly 1000 g daily for 57 days, followed by weekly injections for another 34 weeks, and then monthly injections

Injection site irritation: Redness, swelling, or itching at the subcutaneous injection site is the most frequent issue

Moderate to severe infections often require oral or IV antibiotics

PMID: 175 Sinisterra LoaizaLIFernndez-EdreiraDLiares-BlancoJCepedaACardelle-CobasAFernndez-LozanoC
