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doi: 10.1146/annurev.bi.61.070192.001515
Infectious etiologies of parkinsonism: pathomechanisms and clinical implications
The expression of adhesion molecules on endothelial cell surfaces induced by TNF- has also been shown to be inhibited by sulforaphane via the inhibition of the activation of p38 MAPK (not JNK), and, interestingly, this effect is not mediated via Nrf2 expression [129]
Their structure includes multiple hydroxyl groups that facilitate the neutralization of free radicals, decrease oxidative stress, and modulate nitric oxide bioavailability, potentially enhancing endothelial function and metabolic health [340]
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