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Description
This heterodimer translocates to the nucleus, where HIF-1 binds the activating protein CREB ( P300 ) and the hypoxia reactive element ( HRE ), and subsequently initiates a series of hypoxia-induced cascades, including angiogenesis, through increased transcription of target genes, such as VEGF 28
2021;4(10): e2128568
STORAGE Lyophilized -20 C 24 months Reconstituted 2-8 C, 14-28 days PEER-REVIEWED EVIDENCE Schoenenberger GA, Monnier M
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