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Western blotting of separating nuclear and cytoplasmic extracts revealed a significant increase in FOXO4 expression in H 2 O 2 -induced senescent TM3 Leydig cells, and confirmed that FOXO4 protein was concentrated in the nucleus (Figure 3C3E)

A box was constructed to fully enclose the small molecule and protein by adjusting the Grid Box parameters, followed by running AutoGrid 4, setting the docking parameters and algorithms, running AutoDock4, and exporting the results file in PDBQT format

In many of the above studies, patients were reported to have subnormal B12 levels

Histology confirmed increased angiogenesis, greater fibroblast density, and improved collagen organization

Furthermore, it is reinforced that after being surgically resected, primary intestinal DLBCL with high c-MET copy numbers was associated with an unfavorable prognosis [19]