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Yes, but only as a research chemical

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Astrocytes release GSH into the extracellular space and -glutamyltranspeptidase breaks down GSH to a cysteineglycine dipeptide and glutamate

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6a) and increased Gclc/Gclm expression (Fig

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To further verify that the catalytic activity of LOXL2 was responsible for the increase in BHZ signal, we used the following negative controls: (1) the overexpression of catalytically inactive H626/628Q LOXL2 double mutant (LOXL2-DM) 39,40 , (2) inhibition of LOXL2 specific activity using the small molecule inhibitor PAT-1251 (10 M) in cells overexpressing catalytically active LOXL2 41 , and (3) inhibition of total LOX activity using the non-selective small molecule LOX inhibitor -Aminopropionitrile (BAPN

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2% Arbutin works to improve the appearance of dark spots and uneven tone, while 0.7% Glutathione, a potent antioxidant, supports radiance and a clearerlooking complexion

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