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Description
Thioredoxin-1 attenuates indomethacin-induced gastric mucosal injury in mice

demonstrated that oral quercetin-based supplements were clinically effective, well tolerated, and provided significant symptomatic improvement in patients with clinically proven interstitial cystitis (IC) [102]

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However, if you have a sensitive stomach, taking it with a small meal or healthy fats is also perfectly acceptable and may help with the absorption of fat-soluble nutrients you are pairing it with
Piecuch M, Garbicz J, Waliczek M, Malinowska-Borowska J
