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Aside from its role in catecholamine catabolism, COMT converts an antiestrogen compound (2-hydroxyestradiol) to a proestrogen (2-methoxyestradiol) and leads to an estrogen-rich environment
doi: 10.1016/j.cmet.2017.11.002
Vitamin C stimulates sphingolipid production and markers of barrier formation in submerged human keratinocyte cultures
It plays a particularly strong role in the gut, acting throughout the digestive tract to aid digestion
