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in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )

The compounds selective mechanism and lack of off-target effects support its safety profile

(Endocrinology, 2001, N=obese mice and in-vitro assays) confirmed that AOD-9604 stimulates lipolysis and inhibits lipogenesis through mechanisms independent of the GH receptor, meaning it does not drive the IGF-1 surge seen with exogenous GH [1]

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Vitamin B12 is essential for keeping your central nervous system healthy, making red blood cells, and creating DNA