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Thus, ASD is characterized by an imbalance of the processes of mitochondrial fusion, fission, and mitophagy that leads to contamination of the brain with dysfunctional mitochondrial fragments, insufficient energy supply to the brain tissues, and as a result, impairments of memory and synaptic function [187] contributing to ASD pathogenesis

The pathophysiology of mitochondrial cell death
26(15_suppl):5528

Without sufficient glutathione, the detoxification burden can manifest as fatigue, headaches, brain fog, and the general malaise that some patients attribute to the medication itself