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Oncotarget, 8(31), 51907

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B.NathansonK

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The biosynthesis of carnitine depends on lysine and methionine, and requires a variety of vitamins and minerals as cofactors

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Yeast expression systems for human CBS mutants have also demonstrated that chaperones can promote proper assembly and tetramerization, supporting mutation-specific therapeutic potential (75)

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Some chemotherapeutic drugs use specific transporters to enter cells (72), and any mutations in these transporters can inhibit uptake and decrease drug absorption

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