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Comparison to Other Needle Sizes Larger needles like 25G or 23G are thicker and more painful but offer no additional benefit for peptide injections

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doi: 10.1182/blood-2017-10-809293 43 BuschLMougiakakosDBttner-HeroldMMllerMJVolmerDABachCet al

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Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs

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