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Some drug-drug combinations may be contraindicated

Heres what we know, what we dont, and how to think about it in practice

Because of the ability of Norleual, another AngIV analogue to block the action of HGF on c-Met (Yamamoto et al., 2010) we hypothesized that increases in spine density initiated by Dihexa and Nle1-AngIV are mediated by the HGF/c-Met system

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Nevertheless, their mildness and stability in neutral pH systems make them valuable for gentle anti-aging or post-procedure formulations
