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Reciprocally, environmental chemicals can interfere with the composition (Figure 1c) and/or metabolic activity (Figure 1d) of the GI microbiota, with potentially deleterious consequences for the host

2 The adenylation loop abuts the E-flap moiety, which is a conserved loop containing a catalytic glutamate that can close over the amino acid and ammonia half-site of the active site (Figure 1)

[DOI] [PubMed] [Google Scholar] 37.Cazzola M., Calzetta L., Page C., Jardim J., Chuchalin A.G., Rogliani P., Matera M.G

D., and Weinberg J
