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Targeting oncometabolism to maximize immunotherapy in Malignant brain tumors

PEGYLATION: An important approach for novel drug delivery system
By examining the promoter regions of HRG, we identified potential HIF-associated higher-order promoter regulatory structures, known as Multiple Organized Regulatory Elements (MORE cassettes)

In addition, these beneficial effects correlate with the counteraction of the isoprenaline-induced increased lipid peroxication products in the heart tissue and reduction of all of the necrosis markers commonly measured

One prominent example is Keytruda, the PD-1 neutralizing antibody used in cancer immunotherapy
