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The recommended starting dose of Ninlaro is 4 mg once a week on days 1, 8, and 15 of each 4-week cycle along with Revlimid and dexamethasone

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In ALS, there is an abnormal cytoplasmic aggregation of misfolded proteins, mainly DNA-binding protein 43 (TDP-43), and fused in sarcoma (FUS) (Wijesekera and Leigh 2009)

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