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They include various free radicals and reactive molecules formed from molecular oxygen and nitrogen, including superoxide anion radical (O ), hydroxyl radical (OH ), hydrogen peroxide (H 2 O 2 ), singlet oxygen ( 1 O 2 ), nitric oxide (NO), and peroxynitrite (ONOO ) [28]

This polymorphism results in an amino acid change from alanine to valine, which prevents optimal functioning of the enzyme at temperatures above 37 C

Separate from strong acids or high-strength vitamin C

Diagnosis generally requires an MR arthrogram of the hip joint in question

Molecular docking studies revealed that compound 17 has strong interactions with critical amino acid residues within the active site (by hydrogen bonds with Glu1261 and Glu802)