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Indeed, the expression of the GSTP1-1 variant Ile105Val is able to increase the effect of lead on the development of ASL 66

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These belong to a class of drugs called incretin mimetics , which either mimic or enhance the effects of gut hormones that regulate appetite and metabolism

This suggests that regulating the FTH1/TFR1/GPX4 signaling pathway may inhibit ferroptosis as a potential treatment for depression