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Fine tuning TLR signaling

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Thus, it impairs Ca 2+ efflux through L-type calcium channels, resulting in a reduction in efflux Ca 2+ and an increase in intracellular Ca 2+ , which affects the systolic and diastolic functions of cardiac myocytes (44)
Current NICE guidance (NG49) emphasises lifestyle modification as the primary treatment for NAFLD, including weight loss, dietary changes, and increased physical activity

Schley, G
