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This increased susceptibility for cell death in G6PD-deficient cells can lead to adverse physiological effects under conditions of increased oxidative stress in tissues where the specific cell type is indispensable (44, 45, 48, 75, 101, 105, 111, 115)

Trends Food Sci Technol 10(67):199204 Yokogoshi H, Kato Y, Sagesaka YM, Takihara-Matsuura T, Kakuda T, Takeuchi N (1995) Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats

In a number of works with various cell types, it has been shown that disturbance of the GSH/GSSG balance caused by accumulation of GSSG caused by an oxidant precedes the induction of mitochondrial apoptotic signal [58-61]

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