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Visual inspection is unreliable: aggregation and oxidation occur long before cloudiness appears

Endothelial cell-surface gp60 activates vesicle formation and trafficking via G(i)-coupled Src kinase signaling pathway

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Placing sipes in a block increases flexibility that can reduce noise levels, says Richards, but the slits create smaller blocks that provide additional sound-generating sources at higher frequencies. Kenny says tread designers intentionally vary the depth of sipes for noise control

(Chan et al., 2017) successfully increased the stiffness of the material to match that of the native nucleus pulposus by incorporating poly (-caprolactone) (PCL) reinforcement into carrageenan gels, providing a possibility for nucleus regeneration