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This underdiagnosis can lead, besides death in 20% when it is not appropriately treated, to Korsakoffs syndrome, a severe dysfunction often following untreated Wernickes encephalopathy, that does not remit even with thiamine treatment and is associated with chronic alcohol abuse and chronic thiamine deficiency (28)

Application of methylene blue -vitamin C N-acetyl cysteine for treatment of critically ill COVID-19 patients, report of a phase-I clinical trial

PMID: 281 ShahS.ChestiA.RatherM.ManzoorS.MalikR.KhanJ
