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Further, MOTS-c enabled 17% of the old mice to enter the final running stage (highest speed), whereas none in the untreated group were successful (Fig

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Transforming growth factor (TGF)-, a cytokine that is responsible for a wide range of renal cell pathologies, has also been shown to stimulate ROS generation in an NADPH oxidase-dependent manner in pre-glomerular vascular muscle cells (Sharma et al., 2005)