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Thus, we used the 7 nAChR blocker MLA to confirm its function on pain and found that MLA reversed the analgesic effect of nicotine

3.2.3 FUNDC1 mediated mitophagy The FUN14 domain-containing protein 1 (FUNDC1) is widely present on the mitochondrial outer membrane and acts as a regulator of mitochondrial autophagy in response to hypoxia, inducing Parkin-independent mitophagy (Liu et al., 2012)

Both approaches show effectiveness, with selection depending on injury characteristics
Seasonal adjustments
