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Research shows that increased SAM levels help regulate how the body uses energy, particularly within fat tissue

Mov Disord 26:558559 [DOI] [PubMed] [Google Scholar] Santos-Garca D et al (2012) Polyneuropathy while on duodenal levodopa infusion in Parkinsons disease patients: we must be alert

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In 1986, the respective roles of HSL and MGL in TAG hydrolysis were clarified when isolated HSL was found to hydrolyze acylglycerol with an accumulation of MAG in vitro, whereas glycerol release was blunted through selective removal of MGL by immunoprecipitation (31)

Unlike GLP-1 agonists such as semaglutide or tirzepatide, which work primarily through appetite suppression, AOD-9604 directly enhances fat metabolism at the cellular level through beta-3 adrenergic receptor modulation