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Nanomaterials themselves as therapeutic drugs and more advanced nanomaterial design While nanoparticles have been widely studied primarily as carriers for delivering drugs, the value of nanoparticles extends beyond designing them into drug delivery systems

This modification enhances NNTs affinity for its substrate NADP+, promoting NADPH synthesis, maintaining ironsulfur cluster homeostasis, lowering intracellular ferrous iron levels and lipid peroxidation, and thereby protecting tumor cells from ferroptosis (118)

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