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Description
Targeting Becn1 to inhibit autophagy significantly restores the levels of serine protease GZMB/granzyme B within target cells under hypoxic conditions and induces tumor regression in vivo by promoting NK cell-mediated tumor cell killing (109, 110)

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the selection should be driven by the target outcome

Glutaminolysis Glutaminolysis is a pathway of incomplete glutamine oxidation that occurs in immune cells (39)

Researchers have explored its role in GH/IGF-1 axis modulation , appetite-related pathways , and metabolic signaling in animal models
