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At low concentrations of Asc (less than 20 mmol/L), chloroplast APX activity is rapidly decreased in the presence of H 2 O 2 , with an inactivation half-life of the 30 s

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However, when roasting was combined with reverse-pressure sterilization, allergenic responses were significantly reduced

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As recently demonstrated by Mosteiro and co-authors [155], the thyroid is strictly dependent on Notch for its homeostasis, and Notch inhibition promoted the destruction of thyroid function, with upregulation and downregulation of selected genes, including a decrease in PAX8 expression in both mouse and human thyroids