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Bicuculline is a competitive antagonist of GABAARs primarily on the ionotropic GABAARs, ligand-gated ion channels, and the passing of chloride ions across the cell membrane [230]

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It is useful as a reference point because both Sermorelin and CJC-1295 act through the GHRH receptor

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Van HMJ, Sastre TJ, Sartini D, Emanuelli M, Parsons RB, Martin NI (2016) A rapid and efficient assay for the characterization of substrates and inhibitors of nicotinamide N -methyltransferase