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The Institute of Medicine has not established a tolerable upper intake level of B12 because studies show no adverse health effects when taking excess levels of B12, either through food or supplements

If you have known MTHFR mutations, a history of poor response to cyanocobalamin, or strong preference for methylcobalamin, seeking a formulation with that form is reasonable

The standard dosage is 5 to 10 mg per week via subcutaneous injection

Is It Better To Take B12 or B Complex