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[DOI] [PubMed] [Google Scholar] 107.Sacewicz I., Wiktorska M., Wysocki T., Niewiarowska J

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Cell Death Dis 6:e1587e1587 Kishino A, Hayashi K, Maeda M, Jike T, Hidai C, Nomura Y, Oshima T (2019) Caspase-8 regulates endoplasmic reticulum stress-induced necroptosis independent of the apoptosis pathway in auditory cells

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Despite being derived from angiotensin IV (a true peptide), Dihexa's chemical structure has been extensively modified: it incorporates non-natural amino acid analogs and a hexanoic acid cap that make it structurally distinct from conventional peptides