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doi: 10.1161/hy0302.105221
Under neuroinflammatory conditions, curcumin (5-25 M) can attenuate LPS-induced microglial activation, achieving approximately 60% reduction in pro-inflammatory cytokine release (TNF-, IL-1, IL-6) by suppressing the TLR4/MyD88/NF-B signaling cascade (Zhang et al., 2019)
