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A Category 1 designation can be resolved in either direction: the FDA may determine the compound is appropriate for compounding (moving it to an approved list) or inappropriate (moving it to Category 2)
However, this study only conducted cell experiments and lacked animal experiments
Role of Astrocytes in Maintaining Cerebral Glutathione Homeostasis and in Protecting the Brain Against Xenobiotics and Oxidative Stress Arthur Cooper 6
10.1038/s41418-019-0380-z 225 WangM.MaoC.OuyangL.LiuY.LaiW.LiuN.et al (2019)
