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Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)

Most gut peptide research has been conducted in rodent models, and while the mechanistic data is compelling, translation to human outcomes has not been established through large clinical trials

Long-term safety concerns are lower than for compounds that introduce entirely foreign mechanisms

regular B12 when figuring out which choice matches what they want to achieve
