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doi: 10.1016/j.biopha.2018.10.051 100 UferC.WangC

Some authors have evaluated this condition as being responsible for as much as 24 missed-school days per year for these children, or 15% of their childhood time, with an estimated yearly cost of $170,355

Additionally, MMPs influence the secretion of various chemokines and cytokines, creating a strong chemokine gradient that leads to the recruitment of inflammatory cells to the site of injury (70, 71)