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Local injections also carry a very small risk of introducing an infection into the joint but have the advantage that if gout has not as yet been definitively diagnosed a sample of fluid can be obtained using the same needle and analyzed for the presence of uric acid crystals
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One Cochrane review found that high-dose oral vitamin B12 supplements (1,000 mcg to 2,000 mcg per day) was as effective for correcting megaloblastic anemia as B12 shots
