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doi: 10.1146/annurev.neuro.27.070203.144206
Zhang B., Duan Y., Yang Y., et al., Design, Synthesis, and Biological Evaluation of N(3Cyano1HIndol5/6Yl)6Oxo1,6Dihydropyrimidine4Carboxamides and 5(6Oxo1,6Dihydropyrimidin2Yl)1HIndole3Carbonitriles as Novel Xanthine Oxidase Inhibitors, European Journal of Medicinal Chemistry 227 (2022): 113928, 10.1016/j.ejmech.2021.113928
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Metformin belongs to the class of biguanides, drugs known to lower blood sugar through a beneficial effect of reducing IR and circulating insulin levels
In physiological conditions, selenoproteins participate in the activation of proliferation, differentiation and redox metabolism of T cells
