selenium and glutathione peroxidase metabolism in pigs Role of Selenium-Dependent Glutathione Peroxidases

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Riwes, Mary

In the present study, administration of OMZ decreased antioxidant enzyme activity in the midbrain and cerebral cortex with increased oxidative stress and neuroinflammation in both regions

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1), while the sugar moiety, through its hydroxyl groups, is close to the main chain carbonyls of G323 and R322 in one conformation and with the analogous groups of G437 and Q440 occupying the hydrophilic portion of subpocket A in the other conformation