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Finally, we discussed several biomarkers that can help to assess the BBB permeability and integrity in-vitro or in-vivo and briefly explain their advantages and disadvantages

The effect of it is almost immediate and can last for more than a month

23, 97102 10.3109/09546631003801619 [DOI] [PubMed] [Google Scholar] 87.Handog E.B., Datuin M.S

The findings cannot be directly extrapolated to female pattern hair loss without dedicated meta-analyses No standardised outcome measures: Different studies used different methods to count hairs (phototrichogram, TrichoScan, clinical photography), making direct comparison imprecise Publication bias risk: Studies showing positive results are more likely to be published than negative ones, which could inflate the apparent effect size Need for larger RCTs: The authors themselves call for larger randomised controlled trials with standardised protocols to establish optimal treatment parameters What This Means for Your Hair This meta-analysis provides the strongest evidence to date that microneedling should be considered a primary treatment for androgenetic alopecia not just an add-on to existing therapies